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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a736e74b99217cf560b9ab08ba8c1a972ae4aea943d2046479951295e1133424' 
  AND token = '0Y8RA7mQLiR+80j8DfqrSWZEaR8K/r2vcjWe6Lk18zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}