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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba292eced125969e2865713b9b5d7faa99e257b3b4be31e1c2191e7cf778a379' 
  AND token = 'iiaZ6vwqxLEtXw+Zfu/viM27Y5nvcWT0ERSc8QiawrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}