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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0e1ce1a6ed0ff40de76d9b3b5384d320fbc5612b5ebaa66a2a47e71f990edd' 
  AND token = '1ml2Yxs4QPGFUFG1lsOHnD4DaH8oVPlmHT6WC3HLu20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}