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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9049b14aca12feda6ba69b4c5a171d658fa157970d94b69950c67458f730aaa7' 
  AND token = 'KlrTMSfSHeYJAAmLzZbnLmP7lO+xjQ61hd1xYQLXBmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}