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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f35036ce52cbdc983a20c139815693725e292add490ebb3a11620bcfaac84c6' 
  AND token = 'n4qlQd9F+yfTIxzUiG/p+J1k2Pwql5mmnw8+bjJ4cvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}