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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d8c4912c9ee986440603e366f380cbb1901ac445f006ff6e2ecb8dcd8606dd' 
  AND token = '1r/KmeK4Hp+1gfF3+aQEmeAdx1pH5cJs2QEFBO19BCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}