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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5359268eaf03b43fa3d71bd5de946f8b62682d185f6ecf2906b42b883c0ba13' 
  AND token = 'DOZ/PTktO4qpBgyb2tsEDfo2QL+Go7bNlEGSh/Q0Y/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}