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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b299ea11d371974ea1e29339e7053a8e387f732f469e8cf0e4fa543bb644b3bf' 
  AND token = 'ndUs4R8Ldx/WYKJeF4X6DUeRWefZBYyHNzIkdocDb4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}