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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21db9d171421a913429228b4b26e6c7cdb55c28dccae4119373bb5a16d8a51ef' 
  AND token = 'j2+dyVL8+vVgA0jeBYK0crFechQA3sWJG0LyBT6NEfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}