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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c300de539e10d7de7f351622c864c073f8853500ad3a45928c367d0d7c676f71' 
  AND token = 'NlHDimaiiLkSbUPDxlKH/N888d68h0HjJa0MgffgYqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}