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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f6396e5e096bf6cc6a4e31406fca2d37e3feb43366c1db50f2fa94daea2cab' 
  AND token = 'Pt7ew8Rh4fKTLNjYxRV5DfCEjSiRe04g6zaKd0N5oV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}