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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5993f0cf4729cd9b12240c1fd80dbe1935cd4059ed088a37239e5b5854dcdde2' 
  AND token = 'zpQ8GTRkQGq9ddTr0h7I0xfuaFO1FT7Ny7cf00XKFdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}