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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2008dbe3eabb6b09508ef1d1a70755dae9c5b81cdfe8bc6b882d2c151a1cf669' 
  AND token = 'KHdXxrv0GjBkzWr57pN0cBYkVn0Hg8+XOLV/pRInyNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}