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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e437f37fc67612c9194673b3dd3df4aaab6a2ffd7ca504ca51973c387bf256e' 
  AND token = 'FHvNw4gJPgCzaQ+SRsB/QrSElLofNDFD5bEUS5Ap2sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}