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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa722b19595a21d66d5dfce1b6f75015ef24f5038d15b1245260c985d9aa250' 
  AND token = 'a4pSi7F/4jQVFLh/Tj0wRlzMT3/1qafBUqPDmmcEN80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}