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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eea0988abf8e9c8a040c1fe2b1d5a6d14b5bc1020e4cfb0100b68bd4942a4a9' 
  AND token = 'EAW7cBOENbbOv9UloIT36ygW/lRyiPPz+v6EFjEUKnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}