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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7cf4e8ce4db5ff20ba3a57eb3871839c915a1c47fef5225868fa7b26314e72b' 
  AND token = 'v5vcodTpw0qy2jfMOWMBKlrBGrN5jS9+aNBQ+4Qr6g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}