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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd010d16ddff7526262a299034888fe27eb54fdeb22ca0837bbebf57186aeb63a' 
  AND token = '1+510gdWZgIIeN/hRdVhoVO/1N2QXZtzmtXu2Jz3VBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}