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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '061fe7ce353246cbd625e2f1c111a57a11248a50bfff5e1c4f91bcab38f01cff' 
  AND token = 'la8tdbbL1Df2CCQsMk/umeBMNsVbbwsBiHJCi9raNo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}