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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae9de5e69a4ac21c7c4060a9f7a381ddb720370b404b75a04f5ba31dd4f627f' 
  AND token = 'uN3sZUmT5zktmftsF+4GuJwE3XsPFbbM4hyepYXKH3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}