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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acb294d9293b1f603b51fa5bb77a6802dc49b569e31b6063074e4101c60b8fd' 
  AND token = 'nCEx/1okPwpfuvJ17opnIB/c5U4Guy5ybcbwlq1BZ58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}