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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b626b63ed0ad284a0701b19eb4069eac2f6646eb57af6b90bc4665720969bfe' 
  AND token = 'J4KJJ1rk26+1cZZmzngaez9G0ll/KfMqw47ttXXCosg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}