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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14ab5e767631fed0529670463a4528a01e900adde19fb7e233ae9a278169879' 
  AND token = 'dVkCxu+W7zw8EUhNaWF6C1XU0nlkpZlhaTlqmVtwtSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}