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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a537da2633e70597fe83bd7bcc724557ec64902796ddb01b70fde899c3d390' 
  AND token = 'z2mPpOdos20M00/t5yA/Q5OaQCxcOjs4OjRANvSJ5v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}