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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6d4c0eb13493b635ae52f7befee38f19fa60603ef93db6c70d241f917886ac' 
  AND token = 'Aagi2EhVHmvK071kmC+2DIAcO3PpYqwzvdmHyc6tUOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}