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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af03557dfe8f40b0eea7fe89b3c81ca3d8f013f620f46572481bebc76b5346f' 
  AND token = 'bhKajPn5pJZu6s/HmrdT0+NB9a3ePxqEJ5VdatLGbBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}