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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2d3082fcc470fd1bb71be4a6f3bb494499618ddaf0df7e5da083717e610fb0' 
  AND token = 'CsOpfjiiS7u1N9zHKRU8yG5ilXaAMDfsfZv7dBt4J3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}