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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df4d9b4b6e6a29c321265004f291161e8405e8f882d7f705e1fbcc29374bde5' 
  AND token = 'VU0x15uezSjh+Azs9DlELnKarUhjwWme4B1jeznucbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}