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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fb54b413108295524c1db04d1553724d9ca2d90cc5a2548ad51b253c979825' 
  AND token = 'YT49dVPktGd37z++m6A+8sN17ZMDlDld9j0Zj6U1y2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}