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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c2e9e2c497344508b56c64dd86f1674c83fea8f82822c4e4d858136d3f9c2e' 
  AND token = '9E1NJ+oAWIXBb8gPPc9NsMBgqXxUUoOZMDoWk2lWpGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}