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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0ebef0612b3e3182eaad0aeecd25628ac08cead0242146d6730c68e53dff284' 
  AND token = 'sL6NYJBZLLxcjxX0jfxmHo0GhyqBnoKPUVWAVv+dD3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}