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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81f027365e34f7c5b0c71b6de524426d989b4287c9423f00b4ca2380a991298' 
  AND token = 'E6hGNxb1kOhReVq9GY3r5CN20S3X6O5RJk3vsErcJZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}