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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6f21660a89362089c7af3db607822d04d3ccb3df8430eb7246bfd34c3fd173' 
  AND token = 'Hfxb8dH8yE7cWCPV14vazCoQg3NxLEKZ+uz5ueBps6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}