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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b5f9125a4e30688ab54d1d2e580b8c36d3b82b49ac9e0067c26836af3e2405' 
  AND token = 'g+Ob8agS/UvOhL7Rpb00xthk/q++0yvJGMLHrDihyP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}