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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75d74c2872d324c524eb103bc4378c7f22e81234947c08b277ce7eea864245c' 
  AND token = 'hpe5Hshi/c73r6idnoG1b7BDqa+qmxAhHnHHqarTPJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}