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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac78f8fca90c8cf03a4d46bfcd9194bbff9fab12aff4796d51366fb6c41ab08' 
  AND token = 'bgaNx9qKPyg+3kG/9xoEKaQ/mEI1KKthydFEod1wSKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}