SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301419edecf13f4af2446f5b7d8b39f0b7ed27a3d35f9149772f12fddc10f874' 
  AND token = 'iv+lCQ17sr0is41tY4xc3mkpfM3MH+QIFOd3BKtPUZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}