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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af090e4e95a35e0df534578d9b041eaeb1380280af1731379896e054f57df956' 
  AND token = 'V5aIR0J5TZ2WC8PwS+A+0ClpMNICDVsQtnz6iSiFlug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}