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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b150dfd0e9b89f06bce91c2c11139c61870ccf90d3bc7ab8ba17f1e2ed3c2f1f' 
  AND token = 'PUTu0SZ/73RkbkNGKy9BWf8lSK3sles3zaebgAwmuBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}