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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d16c1a0bcd0dc78a7b9cc5e6adcd969269a3440416c585cc00205bc1049781b' 
  AND token = 'CRfZ1HYIjjdI1lwed1B+YIxBcBsnEociWELMiPJiwyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}