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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5500e5e2c508549c665dd8e1e0aeff5b0189027716a4528040316fa8a488da6' 
  AND token = 'uijzgYceoQVUtPD0le3/u2MdjH3VsFlWhXo+SLoTeio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}