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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168d77d11e4a861a7677df56106ce2020efd205158ed4f929379e7aef92d0aea' 
  AND token = 'IzOf1VM4g0reEh0rEG5nMRPdKJCgqEYx17MEsPOUmrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}