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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6f1e44da6b1da05dd06a57a6e5ba2368c5ab4bd9b1a0339e18794b689375ca' 
  AND token = 'NquYYaTvUX6oAoyTvG6dsgY1If+yhGdBqHcMazLY5dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}