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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33156f1415289e40bd6d175fd4c1b63b171d149e9257a4e54046d898bccc7294' 
  AND token = 'UxaZ/Oyax5JdkgnxJuwEo3q5bWWPg8xiv2AfVykFCeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}