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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7cfc48c6bf265e287f81aa9ec223693fd503ac5a2b226a538b5f2800f89926' 
  AND token = 'pBlX6/JciJJawZFFaJ7BMjdW8RT+6sPE8IfVu+JdxqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}