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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b75615e0b20984bc6e5ef7c5e7ea62a6b36de1035e78a8642a2cb381c6b8dd7' 
  AND token = 'EpEoEusnUveczXXuGc6cGhAtwblnRfVUhxoEdKjWUC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}