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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3efbedcf6ce0eff2caf5f4979bbd486d3045675a08c481a77b7870c6b5c06722' 
  AND token = '0r5y5r2gmrIXrppg7GZ5p+wHmc7tPV9ry+Csrrdbhq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}