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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad826070ad5b1dacc3be89ace9d7f29c7ed097f3480f8def9e05cedc8590678' 
  AND token = 'aJc0P9AQaOfracPGTZMKU3CHhUlJFaQDvcJEGTsW4WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}