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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fbbf8233111ce6820f349c0baf2273aa1965fe911f7b2eb42506cb9bb2de6a4' 
  AND token = 'hfVhGBRuuzecIFPlAtz4gDj49GS9Msh1iE6j/qi/W5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}