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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e6b87b9fc89f4619ac27cdbcb90a35d270feada1eb3aaa755afba2798bf4ee' 
  AND token = 'b3qtsGUNMe9MNYHmn6OQSXyIA/MtNORx6EcCUZc3MRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}